Radio resource allocation and call admission control are studied in heterogeneous wireless network. A theoretical model of allocating bandwidth and connections is proposed on basis of non-cooperation game theory. Combining with the utility function of network connections, the existence and uniqueness of Nash equilibrium in the processes of non-cooperation game allocating is proved. Furthermore, a call admission algorithm is presented to ensure communication reliability based on the analysis of relationship of traffic intensity and block probability. Simulation results reveal that the allocated mechanism resolves the issues of allocated bandwidth and connections. And it ensures the reasonableness and fairness in general. In addition, the results also show that the call admission control algorithm could guarantee the communication reliability by dynamic adjusting allocated number of connections.