In cloud environment, all kinds of idle resources can be pooled to establish a resource pool, and different kinds of resources can be combined as a service to the users through virtualization. Therefore, an effective scheme is necessary for managing and allocating the resources. In this paper, economic and intelligent methods are employed to form an intelligent resource allocation scheme based on double combinatorial auction with respect to the characteristics of resources in cloud environment. In the proposed scheme, a reputation system on the basis of quality of experience (QoE) is devised, and the reputation attenuation coefficient and the user credit degree are introduced to decrease the negative effects of malicious behaviors on resource auctions, providing QoE support to resource dealing. In order to determine bidding price rationally, a bidding price decision mechanism based on back propagation (BP) neural network is presented to comprehensively consider various influence factors to make price adapt to the fluctuating market. Finally, due to the fact that the problem of winner determination in combinatorial auction is NP-complete, a group search optimization algorithm is adopted to find the specific resource allocation solution with market surplus and total reputation optimized. Simulation studies are conducted to demonstrate the feasibility and effectiveness of the proposed scheme.