Multi-replication definition (MRD) is a new trend of database replication, but it will increase the propagation costs. In this paper, three optimized propagation algorithms for MRD are presented, D-M, ILS and LIS. D-M Algorithm gets the minimum individual propagation cost by dividing replication objects and merging propagation objects. Based on it, ILS makes the total costs to the least in strict Chain Topology scenarios, and LIS gets optimized total costs in other common situations by decomposing the propagation task. Their correctness and efficiencies are validated both theoretical and experimentally.