In this paper, the authors discuss IS-Global's pivotal technique in design and implementation. IS-Global is a relational multi-database system, which provides an integrated global information system platform for enterprises applying CIMS (computer integrated manufacture system), and hides the detail of the heterogeneity of network, local operating systems and database systems. The major characteristics of IS-Global are as follows: (1) It is a tightly integrated system with unique global schema. (2) Being a multi-user system, IS-Global possesses two-lever client/server architecture and supports concurrent and security control mechanisms. (3) IS-Global provides graph-based tools, ODBC function call and interactive SQL interface. (4) IS-Global supports multi-location queries.