With the development of network and multimedia technologies, many new networks are emerging and converging through the Internet, making the network more ubiquitous, open and dynamic. And nowadays the mismatch between the explosive growth of dynamic and distributed content and the personalized needs of users in the network is increasing. Therefore, giving the large-scale contents in the network environment, how to provide personalized, intelligent content services has become the common issues in research community and industry. The purpose of this study is to combine semantic technology and network communication mechanism to support personalized and semantic integration services in the open, dynamic network environment. This paper proposes a self-organizing semantic integration framework with key techniques of realization mechanism for the dynamic, distributed contents, which includes the relational routing model, the technology framework and implementation process of self-organizing semantic integration. The framework supports building the personalized, intelligent integration applications suited to the dynamic and distributed contents, and provides the engineering design and technical realization methods for semantically integrating the dynamic and distributed contents in network environments.