In order to extend distributed computing environment and support system integration, the authors are doing some research on multi-agent distributed integrated middleware CSE/MA to provide a general developing architecture of C/S applications for application developers and support developers to bulid various C/S applications easily. Firstly, this paper provides the architecture of CSE/MA, and discusses the components, principal and process of the applications developing with CSE/MA. Secondly, it introduces the services and implementing algrithoms about the management kernal of CSE/MA——register, and provides implementation framework of service agent and requuest agent and their design and implementation. Finally, it concludes the technical features and importance of CSE/MA。